Lecture
Next Generation of Unisart® Membranes – Multiplexing with Unisart StructSure®
- 10.04.2024 at 14:00 - 14:30
- ICM Saal 4b
- Language: English
- Type: Lecture
Lecture description
Ever since the Covid-19 pandemic hit the globe, awareness for point-of-care diagnostics has grown tremendously. Fast, affordable solutions to diagnose infectious diseases help to contain the spread thereof. Multiplex lateral flow assays facilitate the analysis of several biomarkers in parallel.[1] Structured membranes provide an innovative multiplexing lateral flow immunoassay platform. Through assay miniaturization resources such as time, money and raw materials can be saved. Other traditional multiplexing formats such as multiline and para-channel assays suffer from problems with signal intensity for the former or high consumption of raw materials in the latter. This gives structured membranes the edge when it comes to high quality sustainable test development.
In this oral presentation the advantages of structured membranes in comparison with traditional formats will be presented. After a brief excursion into the casting of nitrocellulose membranes, the audience will receive insights into the development of immunoassays with structured membranes in which a saving of up to 95% of antibodies can be realized. Here dot-based ultra-low volume dispensing is used for high precision test manufacturing.[2] This talk informs the audience on the potential applications of structured membranes such as Unisart StructSure® and may inspire the development of new and innovative multiplexing solutions.
Literature:
[1] Anfossi, L. et al. Multiplex Lateral Flow Immunoassay: An Overview of Strategies towards High-throughput Point-of-Need Testing, Biosensors 2019, 9 (2). DOI:10.3390/bios9010002
[2] Jarling, T. The Next Generation of LFA-Multiplexing on Unisart StructSure® Membranes [White Paper]. Retrieved December 12th 2023 from SCIENION GmbH: https://www.scienion.com/wp-content/uploads/2023/11/SCIENION_Sartorius_The-next-generation-of-LFA_WhitePaper.pdf
In this oral presentation the advantages of structured membranes in comparison with traditional formats will be presented. After a brief excursion into the casting of nitrocellulose membranes, the audience will receive insights into the development of immunoassays with structured membranes in which a saving of up to 95% of antibodies can be realized. Here dot-based ultra-low volume dispensing is used for high precision test manufacturing.[2] This talk informs the audience on the potential applications of structured membranes such as Unisart StructSure® and may inspire the development of new and innovative multiplexing solutions.
Literature:
[1] Anfossi, L. et al. Multiplex Lateral Flow Immunoassay: An Overview of Strategies towards High-throughput Point-of-Need Testing, Biosensors 2019, 9 (2). DOI:10.3390/bios9010002
[2] Jarling, T. The Next Generation of LFA-Multiplexing on Unisart StructSure® Membranes [White Paper]. Retrieved December 12th 2023 from SCIENION GmbH: https://www.scienion.com/wp-content/uploads/2023/11/SCIENION_Sartorius_The-next-generation-of-LFA_WhitePaper.pdf
All lectures within this session
- 12:30 - 13:00Standard Addition for Immunoassays - New Possibilities for Quantitative Lateral Flow Tests
- 13:00 - 13:30From Complex to Simple: New Compact Lateral Flow Test Systems
- 13:30 - 14:00Nucleic Acid Extraction Through Zwitterionic Nanofibers Integrated in Flow-Through Micro-Paper-Based Devices
- 14:00 - 14:30Next Generation of Unisart® Membranes – Multiplexing with Unisart StructSure®