Lecture
The PRIDE database and ProteomeXchange: Making proteomics data FAIR
- 11.04.2024 at 13:30 - 14:00
- ICM Saal 3
- Language: English
- Type: Lecture
Lecture description
Mass spectrometry (MS) is by far the most used experimental approach in proteomics. The ProteomeXchange consortium (https://www.proteomexchange.org) has standardized data submission and dissemination of public MS proteomics data worldwide. ProteomeXchange resources are committed to comply with the FAIR (Findable, Accessible, Interoperable, Re-usable) principles, support reproducible research and represent the state-of-the-art in proteomics with regards to open data practices.
Within ProteomeXchange, the PRIDE database (https://www.ebi.ac.uk/pride/) at the European Bioinformatics Institute is the most used resource worldwide, accounting for ~80% of all submitted datasets. As a key point, the activities of ProteomeXchange are aligned with the open data standards developed under the umbrella of the Proteomics Standards Initiative.
The perceived reliability of PRIDE and the rest of the ProteomeXchange resources has enabled an unprecedented increase in the amount of proteomics data in the public domain, which is now comparable to other omics fields such as transcriptomics. As a consequence, data re-use activities are flourishing and are revolutionizing the proteomics field. Some inspiring examples of how this data is being utilised by the scientific community will be showcased. Finally, some insights on the upcoming challenges will also be discussed, including the management of sensitive (clinical) human proteomics datasets.
Within ProteomeXchange, the PRIDE database (https://www.ebi.ac.uk/pride/) at the European Bioinformatics Institute is the most used resource worldwide, accounting for ~80% of all submitted datasets. As a key point, the activities of ProteomeXchange are aligned with the open data standards developed under the umbrella of the Proteomics Standards Initiative.
The perceived reliability of PRIDE and the rest of the ProteomeXchange resources has enabled an unprecedented increase in the amount of proteomics data in the public domain, which is now comparable to other omics fields such as transcriptomics. As a consequence, data re-use activities are flourishing and are revolutionizing the proteomics field. Some inspiring examples of how this data is being utilised by the scientific community will be showcased. Finally, some insights on the upcoming challenges will also be discussed, including the management of sensitive (clinical) human proteomics datasets.
All lectures within this session
- 12:30 - 13:00Love your Data - Research Data Management at the Institutional Level
- 13:00 - 13:30Exploring Current Research Data Management Activities in ELIXIR DE
- 13:30 - 14:00The PRIDE database and ProteomeXchange: Making proteomics data FAIR
- 14:00 - 14:30From Target to Product Accelerating the Drug Lifecycle with Knowledge Graphs and LLMs